Serum α-synuclein was found to be increased in children with obesity and type 1 diabetes (T1D), which was linked to the impairment of executive function in these children. A study published in the ...
Much of the research into α-synuclein, the major component of Lewy bodies in Parkinson’s and other neurodegenerative diseases, focuses on its role in synaptic vesicles and membranes. But could other ...
Yunseon Yang, Jae-Jin Song, Yu Ree Choi, Seong-hoon Kim, Min-Jong Seoka, Noviana Wulansari, Wahyu Handoko Wibowo Darsono, Oh-Chan Kwon, Mi-Yoon Chang, Sang Myun Park, Sang-Hun Lee Proceedings of the ...
The reduction of α-synuclein, which is central to the pathogenesis of Parkinson’s disease and other α-synucleinopathies, can be accomplished through the binding and selective degradation of its ...
Phosphorylation of α-synuclein at the Serine-129 site (α-syn Ser129P) is an established pathologic hallmark of synucleinopathies and a therapeutic target. In physiologic states, only a tiny fraction ...
Researchers have identified two proteins on the surface of neurons that may help drive the spread of Parkinson’s disease in ...
SHANGHAI, China, 29 April 2025 -- In a comprehensive Genomic Press perspective article published today, researchers from Fudan University and Shanghai University of Traditional Chinese Medicine have ...
Parkinson's disease (PD) and Lewy body dementia (LBD) are incurable and progressive neurodegenerative disorders, with some overlapping symptoms. An estimated 10 million people worldwide live with PD, ...
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