Studies have uncovered that abnormalities in the alpha-synuclein protein are likely a causal factor for numerous diseases, including Parkinson’s disease, multiple system atrophy (MSA), dementia with ...

The results of studies in live mice and in mouse and human brain tissue suggest that one of the normal functions of alpha-synuclein, a protein found in the characteristic Lewy bodies that form in the ...

But alpha-synuclein's function is not well understood. A new study led by investigators at Brigham and Women's Hospital, Harvard Stem Cell Institute and the Broad Institute of Harvard and MIT shines ...

One of the hallmarks of Parkinson's disease (PD) is the accumulation in the brain of a protein known as alpha-synuclein. A new study shines new light on the role of alpha-synuclein, uncovering a new ...

Scientists have carried out an extensive study of a newly discovered mutation that can uncover new insights into the molecular basis of pathology formation in a family of disorders that includes Lewy ...

1. Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL, USA 2. School of Medicine, Nephrology Division, University of Alabama at Birmingham, Birmingham, AL, ...

Amsterdam, NL, November 13, 2019 - Aggregates of the protein alpha-synuclein arising in the gut may play a key role in the development of Parkinson's disease (PD). Investigators are testing the ...

Serum α-synuclein was found to be increased in children with obesity and type 1 diabetes (T1D), which was linked to the impairment of executive function in these children. A study published in the ...

Parkinson’s disease and Lewy Body Dementia are two serious brain disorders that affect millions of people around the world.

Every drug approved for Parkinson’s disease does the same thing: it manages symptoms. None slows the underlying destruction ...