Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

Brain cells grow faster in children with some forms of autism due to distinct changes in core cell signaling patterns, according to research from the laboratory of Anthony Wynshaw-Boris, MD, PhD, ...

Researchers have identified an unexpected mechanism that links age-related stress to the decline of blood-forming stem cells.

Modeling the economic impact of a CIZ1B biomarker blood test for lung cancer screening in high-risk populations. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I. This abstract ...

A newly discovered type of liver cell may hold clues for treating severe liver disease, according to a recent study from the University of Michigan Life Sciences Institute. The findings, published in ...

Throughout evolutionary history, there have been genetic elements that have duplicated - giving rise to genes with different functions. These are called 'paralogs'. They are able to form and evolve ...

A key molecular dynamic could be the key to fighting tumors while allowing patients to still receive life-saving cell ...

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

A new preclinical study from Weill Cornell Medicine found that the protein caspase-5 (CASP5), long thought to be a foot ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

The embryonic receptor "Smoothened" regulates dopamine and acetylcholine timing to control learning and habit formation in ...