Humans have about 3 billion DNA bases in their genetic makeup. However, most of it does not encode for protein.

Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

Scientists have uncovered new genetic causes of diabetes in infants, pointing to a region of the genome that has long been ...

A single DNA letter, inserted into a stretch of the genome that doesn’t code for any protein, was enough to turn genetically female mouse embryos into anatomically male mice. The experiment, published ...

Learn how small mutations in non-coding DNA can alter sex development in rodents.

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. Researchers, using an experiment that elucidated the function of tens of thousands of noncoding ...

A study shows that changes in noncoding genes can trigger autoimmune diabetes in infants by affecting hundreds of ...

Like islands scattered across a vast intergenic sea, the nearly 20,000 protein-coding genes within the human genome represent a mere 2 percent of its 3 billion base pairs. When, where, and to what ...

Remarkably, 98 percent of our DNA does not code for genes. Once considered “junk DNA,” it is now well appreciated that these ...

Researchers at Bar-Ilan University have discovered that changing just one letter in DNA can completely alter sex development ...