Engagement of intracellular targets is often critical to drug mechanisms. Establishing a target engagement (TE) profile is an important step in small- molecule drug discovery as well as chemical probe ...

Scientists need cellular assay technologies that examine multiple parameters at the same time, optimize high throughput workflows, control atmospheric conditions, and reduce experimental variability.

Cell-based assays are used to study genes, proteins, and whole cellular functions, as well as the mechanisms that control them, by measuring specific cellular parameters. They have become an important ...

Though HTS and Automation Have Lowered Revenue Potential, Market Is Still Thriving The diversity of biomolecules present in human cells and the need to characterize their presence in normal ...

Cellular assays provide researchers with powerful insights into biological processes, including wound healing. However, scratch assays, the staple cell-based screening method in wound healing research ...

Evaluation of interferon-alfa 2b in a model of acute respiratory distress syndrome and pulmonary fibrosis induced by intratraqueal bleomycin in Wistar rats This is an ASCO Meeting Abstract from the ...