Maintaining the required solubility, stability, efficacy and potency of an engineered biotherapeutic protein is critical after its expression in a recombinant system. Analysis and optimization of the ...

Because the technique provides such significant benefits, and because the transitions (phase changes, chemical reactions, etc.) observed in a sample as it is heated are often very complex, the ...

Differential scanning calorimetry (DSC) is a thermal analyses method for determining how much energy a sample absorbs or emits as heat capacity. The phase diagram, entropy, enthalpy, and thermal ...

Most biotherapeutic molecules include either proteins or protein derivatives, with monoclonal antibodies (mAbs) representing the largest group of biopharmaceuticals on the market. Antibodies have a ...

A paper appeared in International Journal of Pharmaceutics. A team of researchers from Kazan Federal University, Russia, led by Dr. Igor Sedov, reported an application of capillary differential ...

image: A team of researchers from Kazan Federal University, Russia, led by Dr. Igor Sedov, reported an application of capillary differential scanning calorimetry technique for the study of the binding ...