The ventral hippocampus is a crucial brain region in the neural circuitry that regulates mood and anxiety. Adult-born neurons in the dentate gyrus of the hippocampus have been proposed both to encode ...

For over a decade, neuroscientists have been trying to figure out how neurogenesis (the birth of new neurons) and neuroplasticity (the malleability of neural circuits) work together to reshape how we ...

It appears that new cells compete to ‘win’ synapse connections away from old cells, which promotes network plasticity. Linda Overstreet-Wadiche, Ph.D. One goal in neurobiology is to understand how the ...

This report contains a gene expression summary of the dentate gyrus (DG), derived from the Allen Brain Atlas (ABA) in situ hybridization mouse data set. The structure's location and morphological ...

Age-related memory decline may be reversed with high doses of naturally occurring cocoa flavanols, US researchers have discovered in findings that establish the dentate gyrus as central to cognitive ...

Researchers present data and a simple statistical network model that describe an unanticipated property of newly formed, immature neurons in the dentate gyrus. The model resolves a seeming paradox in ...

Our brains are able to store memories of very similar events as distinct memories. This, for example, allows you to find your car even though you parked it in a different spot the previous day, and ...

In a study published in Nature Communications, scientists determine that schizophrenia-associated mutations in synapse-associated protein 97 (SAP97) cause an extreme increase in glutamatergic ...

A research team led by Dr. Àlex Bayés, Head of the Molecular Physiology of the Synapse Group at the Institut de Recerca Sant Pau (IR Sant Pau), has achieved what for decades had been an elusive goal: ...

NEW YORK, NY (October 26, 2014)—Dietary cocoa flavanols—naturally occurring bioactives found in cocoa—reversed age-related memory decline in healthy older adults, according to a study led by Columbia ...