Researchers analyzed pancreatic islets from 299 donors and found that differences in alpha, beta, and delta cell composition ...

PSC-derived cells can reverse type 1 diabetes in mice and may overcome some of the hurdles faced by existing stem cell ...

The gut–islets axis connects nutrient sensing in the intestine with insulin secretion from the pancreas and plays an essential role in glucose regulation. GLP-1 released by intestinal L cells can ...

Professor Deng Hongkui's team from the Peking University School of Life Sciences has made the first successful differentiation of human pluripotent stem cells into fully endocrine-subtype-complete ...

How do living cells respond to physical forces, including those relayed from the complex cellular and extracellular microenvironment within a tissue? We know that these forces affect nearly every ...

Scientists recently developed an efficient way to transplant pancreatic islets and demonstrated that the method can effectively reverse type 1 diabetes in nonhuman primates. In people with type 1 ...

A team led by researchers at Karolinska Institutet in Stockholm has grown three-dimensional clusters of insulin-producing ...

We report on a 43-year-old woman with a 25-year history of type 1 diabetes. Her weight was 53.4 kg (117.7 lb), and her body-mass index (the weight in kilograms divided by the square of the height in ...

CNTY-813, Century’s type 1 diabetes iPSC-derived islet therapy with functional-cure potential, remains on track for IND in 4Q 2026; initial clinical data expected in 2H 2027Upcoming oral presentation ...

The pancreas is an abdominal organ that produces digestive enzymes as well as hormones that regulate blood sugar levels. This hormone-producing function is localized to the islets of Langerhans, which ...