Empagliflozin reduced proinflammatory cytokines and oxidative stress markers in INOCA patients with CMD, improving vascular health. Treatment led to favorable shifts in endothelial extracellular ...
Sepsis is a life-threatening condition that often leads to ARDS, characterized by widespread inflammation and vascular injury. This study identifies lactate-driven lysine lactylation (Kla) as a ...
Characterising covid-19 as “a vascular disease masquerading as a respiratory one” accurately captures its systemic ...
Sepsis, a life-threatening systemic inflammatory response triggered by infection, has long challenged clinicians with its persistently high mortality (up to 40-50% in septic shock). At the heart of ...
A new study uncovers how diabetic red blood cells release toxic packages that damage blood vessels, revealing a promising path for preventing serious complications. EVs derived from RBCs of patients ...
US phase 3 ASTRA (NCT07368959) will enroll across ~12 sites, randomizing patients to a single intracameral administration of ...