FibroBiologics is now evaluating its fibroblast platform in Hantavirus disease models, with particular emphasis on inflammatory cytokine modulation and endothelial permeability reduction. The company ...

Keloids are raised, overgrown scars that can develop after skin injuries or surgery, often extending beyond the original wound boundaries. For many people, keloids are more than just a cosmetic ...

Helmholtz Munich researchers revealed a conserved differentiation process with clinical implications for injury repair, identifying a multipotent fibroblast progenitor in the fascia— the deepest ...

These findings from research into diffuse large B cell lymphoma (DLBCL) are based on analyses of human patients and a murine model. The immunosuppressive role of fibroblastic reticular cells (FRCs) in ...

Fibroblasts play a central role in maintaining healthy tissue structures, as well as in the development and progression of diseases. For a long time, these specialized connective tissue cells were ...

In a recent study published in Scientific Reports, researchers reported that microfibril-associated protein 5 (MFAP5) mediates wound healing through its pro-fibrotic effect by modulating collagen ...

Phase Ia/Ib trial of zongertinib (BI 1810631), a HER2-specific tyrosine kinase inhibitor (TKI), in patients (pts) with HER2 aberration-positive solid tumors: Updated Phase Ia data from Beamion LUNG-1, ...

Regular erections could be important for maintaining erectile function, according to a new study on mice published in Science by researchers at Karolinska Institutet. “We discovered that an increased ...

FibroBiologics developed a transplantable thymic micro-organoid system using selectively screened fibroblasts combined with thymic stromal cells. The organoids are produced through a rapid, three-day, ...