Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development ...

The team observed the emergence of the three-dimensional embryo-like structures under a microscope in the lab. These started producing blood (seen here in red) after around two weeks of development - ...

For the first time, a stem cell model has produced a structure resembling an early human embryo with a yolk-sac-like structure, from a single starting stem cell population and without direct genetic ...

Their findings, recently reported in the journal Nature, overturn longstanding assumptions in developmental biology and could ...