Researchers at City of Hope and TGen (part of City of Hope) have identified a significant correlation between a tumor's ...

In TDP-43 proteinopathies, the RNA/DNA binding protein leaves its post in the nucleus and travels to cytosol, where it’s prone to aggregate. This meandering allows mis-spliced transcripts to ...

A team of multidisciplinary researchers at Cincinnati Children’s and the University of Virginia has developed a computational tool dubbed “SNAF” (spliced neo antigen finder) that they suggest may help ...

Please provide your email address to receive an email when new articles are posted on . Few patients with cystic fibrosis have a copy of the 3849+10kb C-to-T splicing mutation. Research is planned to ...

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been ...

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...