Frailty models have emerged as a pivotal tool in survival analysis, offering a robust framework to account for unobserved heterogeneity and dependence between paired failure times. In bivariate ...

Researchers at the Johns Hopkins University School of Medicine have developed a mouse model that successfully mimics the development of frailty as mammals — likely including people — get older. The ...

Atrial fibrillation (AF) in older adults extends well beyond stroke prevention. Advancing age is the strongest demographic driver of AF prevalence and ...

Frailty can creep up quietly. One year a person is carrying groceries without thinking about it; a few years later, a stumble on the front steps leads to a hospital stay. Doctors have long known that ...