Researchers at the Indian Institute of Science and collaborators used cryo-EM to decode the molecular architecture of a transporter protein controlling the movement of gamma-aminobutyric acid (GABA).

Gamma aminobutyric acid (GABA) is a naturally occurring amino acid that works as a neurotransmitter in your brain. GABA is considered an inhibitory neurotransmitter because it inhibits certain brain ...

A brilliant orchestra brings together many skilled musicians. Throughout a performance, each section must play at the right time and at the right volume to weave a unified melody. If everyone played ...

One of the smallest protein structures ever determined using cryo-EM, GAT1 is fundamental to GABA neurotransmission and its structural determination is pivotal to developing therapies for a range of ...

Dan Brown’s latest thriller, The Secret of Secrets, follows neuroscientist Katherine Solomon as she reports how low GABA, an inhibitory neurotransmitter in the nervous system, expands consciousness.

Artist’s rendering of GABA transporter 1 (GAT-1) embedded in a neuron’s membrane. Tiagabine (green) blocks GAT-1 from shuttling the neurotransmitter GABA (yellow and red) into the cell from the ...

Efforts to better understand how immune cells function hold the promise of providing information that might lead to improved clinical treatments. Writing in Nature, Zhang et al. 1 present results that ...

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The brain is an almost inconceivably complex system of billions of neurons interlinked via trillions of connections that work to coordinate everything you do, think, and feel (Zimmer, 2011). This ...

GABA, also known as gamma-aminobutyric acid, is a natural chemical produced by the brain. It is a valuable anti-anxiety neurotransmitter. When we experience stress, the adrenal glands are triggered to ...

Your body functions using chemical messages that are directed throughout your system with specific targets. These chemical messages are carried by neurotransmitters, which act as a messenger directing ...