Gene expression analysis helps uncover how cells function, adapt, and contribute to disease. Techniques from microarray preprocessing to advanced single-cell proteomics offer complementary insights ...

A new database covering over 100 different canine tissues can significantly enhance our understanding of hereditary diseases and provide valuable information for health research in both dogs and ...

Using genomic and transcriptional data has greatly improved the understanding of multiple aspects of human physiology. A new paper in PNAS reports on molecular-level associations of co-occurring ...

Essentially all cells in an organism's body have the same genetic blueprint, or genome, but the set of genes that are actively expressed at any given time in a cell determines what type of cell it ...

Krystal Biotech reports positive clinical data for KB408 and KB407, demonstrating safety and efficacy in AATD and cystic fibrosis patients. Krystal Biotech, Inc. has announced promising clinical ...

Neuronal specification, expansion and differentiation are tightly regulated by the concerted actions of transcription and chromatin modifying factors that are recruited to regulatory elements in the ...

In vitro data demonstratedself-complementary AAV9 (scAAV9) enabled ~30-fold higher MeCP2 protein expression compared to single-stranded AAV9 ...

Presentation of preclinical data indicating the potential of regRNA-targeting to increase protein levels in a clinically meaningful way, highlighting the company's innovative approach to gene ...

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a ...