For the roughly 3 million Americans living with inflammatory bowel disease, the current treatment options tell a frustrating ...

Researchers have developed a stem cell-based model of the human intestine that may transform how new IBD treatments are ...

Researchers from the Hebrew University of Jerusalem and the Weizmann Institute of Science have identified a previously ...

Years before he conducted the research that would earn him a Nobel Prize in Physiology and Medicine, Shinya Yamanaka, MD, ...

A recent study comparing young and aged mouse intestinal tissues revealed a delicate balance between IFN-γ signaling and ERK/MAPK signaling as crucial for maintaining the intestinal stem cell ...

When inflammation damages the intestinal lining, differentiated enterocytes and crypt base columnar stem cells (CBCs) revert to a regenerative, fetal-like state and form revival stem cells (revSCs).

Live-cell gene tracking: German researchers developed a method to monitor gene activity in living cells over time, aiding therapy development and cellular research. IBD drug screening: Human ...

A new study reported in Nature has determined that the amino acid cysteine could promote regeneration among cells in the small intestine. The work showed that cysteine can activate an immune signaling ...