Tumor-associated macrophages (TAMs) within the tumor microenvironment (TME) exhibit significant metabolic dysregulation, ...

Head and neck cancer remains a major global health challenge, ranking among the six most common cancers worldwide and claiming hundreds of thousands of lives each year. A growing body of evidence now ...

This Scientific Reports Collection welcomes original research on Metabolic reprogramming in immune-mediated disorders. Narrative review articles are also welcomed, to our sister journal Scientific ...

Panakeia ("the Company"), the world's first in silico multi-omics company, today unveiled landmark pathway activation data in cancers at the American Association for Cancer Research (AACR) Annual ...

A recent study has demonstrated the power of metabolic engineering in enhancing the antitumor activity of chimeric antigen ...

Researchers have uncovered how metabolic reprogramming contributes to renal fibrosis in IgG4-related disease (IgG4-RD), a systemic immune-mediated disorder. The review, published in a leading journal, ...

Researchers have discovered a way to make the immune system's T cells significantly more effective at fighting cancer. By blocking a protein called Ant2, they were able to reprogram how these cells ...

Scientists have discovered a way to supercharge the immune system’s T cells by blocking a protein called Ant2, forcing the cells to rewire how they generate energy. This shift makes them more powerful ...

Hoth Therapeutics, Inc. (NASDAQ: HOTH), a clinical-stage biopharmaceutical company, today announced positive data from its HT-VA study, conducted under its Cooperative Research and Development ...

Therapeutic fasting offers a metabolic approach to chronic pain by shifting to fat metabolism, reducing systemic inflammation ...

New study reveals metabolic remodeling as an early event in diastolic dysfunction Restrictive cardiomyopathy (RCM) caused by ...