Oxidation of saturated C−H bonds is a key chemical reaction in synthetic chemistry and chemical industry. Nevertheless, the high bond dissociation energies (BDEs) and weak polarity of C(sp 3)−H bonds, ...
Structural environments of the methionine residues M252 (green) and M428 (blue) in the Fc region are shown. Upon oxidation, these residues are converted to methionine sulfoxide, generating two ...