Randomized trials of platelet function and genetic testing to guide antiplatelet decisions following PCI have produced notoriously mixed results: now, an updated consensus document aims to fill some ...

THE term primary or "spontaneous" hemostasis refers to a complex series of biologic events occurring in immediate response to blood-vessel severance or injury. Although damaged or cut blood vessels ...

PlateletDiagnostics, LLC (PlateletDx.com), founded by Harvard Medical School platelet biology leaders, announced the development of a first-in-class platelet function assay that measures ...

Study of the bleeding tendency in uremia in 26 subjects, 10 of whom were bleeding, showed platelet counts and plasma coagulation factors to be normal. There was a significant inverse correlation ...

Intravital microscopy image from the liver of a mouse model: a platelet (turquoise) adheres to the inflamed vessel wall (yellow dashed outline) and sheds a long, filamentous membrane extension—a ...

Megakaryocytes, which are derived from hematopoietic stem cell precursors in bone marrow, form and release platelets; these circulate in the blood for 8 to 10 days before they are removed by hepatic ...

The coronavirus disease-19 (COVID-19) pandemic that emerged in Wuhan, China, in late December 2019 spread rapidly throughout the world and has caused over 6.5 million deaths. The disease is caused by ...

Managing drug dosage is critical to the overall success of pharmaceutical intervention, not only in the clinic but also in clinical trials. Inadequate dose management of certain drugs can have fatal ...