GLP-1 weight-loss drugs alter brain circuits in the amygdala and dopamine system to reduce the motivation to seek out high-calorie foods.

Could drugs like Mounjaro treat people with cannabis use disorder? They might. Preliminary research indicates they may stop cravings even before people trying to quit feel them.

Stimulating the brain's self-control center via rTMS reduces smoking by 11 cigarettes a day, outperforming reward-suppression ...

We have long been told a simple story about reward: Dopamine is the "wanting" molecule that drives us toward goals, and opioids are the "liking" molecules that provide the hit of pleasure once we get ...

Addiction hits hard. It steals lives and breaks families. Yet, many see it as a sign of weak will. What if we flip that view? Addiction is a brain disorder, not a moral slip. This piece clears up why ...

Harold Lewis has been fighting drug addiction for years, but only recently started thinking recovery could be fun. The 59-year-old former cook earned small prizes — candy, gum, gift cards, sunglasses ...

A new study is challenging one of neuroscience’s most enduring ideas: that the brain’s reward system exists to make us feel good. Instead, researchers argue that it is built to optimize energy.