Systemic sclerosis (scleroderma) causes the body to destroy healthy tissue. It can change the appearance and texture of your skin and affect other organs. Systemic sclerosis (SS) is an autoimmune ...

Localized scleroderma, as the term denotes, is localized to the skin on the hands and face. It is characterized by slow progression and rarely transforms to the systemic type. Localized scleroderma is ...

Scleroderma is an autoimmune condition that causes the skin to become tight and hard. This can change facial appearance, such as the mouth becoming smaller, and affect internal organs. With ...

Sclerodactyly is a tightening and thickening of the skin of the fingers as a result of systemic scleroderma. It can cause the fingers to curl inward and the hands to form a clawed shape. Share on ...

A 55-year-old woman with a history of scleroderma presented after 5 days of experiencing fever, chills and progressive swelling of her right thumb (Fig. 1). The thumb was exquisitely tender to touch.

The management of patients with systemic sclerosis (SSc) can be challenging because disease-associated damage is often difficult to reverse and curative therapies are not yet available. Early ...

Scleroderma survivor, Susan Spence-Le Gendre has been battling the life-threatening condition for over a decade. The discomfort never stops pain, fatigue, weakness, aching muscles, joints and bones, ...