Research on the biological basis of addiction has found that the critical epigenetic enzyme histone deacetylase 5 (HDAC5) limits the expression of the gene Scn4b, regulating neuronal activity and ...

What is craving? Craving is a subjective experience of wanting to use a specific drug. Craving is a core symptom of drug addiction. A craving is distinguished from hunger in being an intense, directed ...

Substance use and substance use disorder differ by the frequency of use and the effect on a person’s life. Substance use disorder is a mental health condition. Substance use refers to using both legal ...

SALISBURY — Every year, around the holidays, families gather to celebrate glad tidings, but for those living with substance use disorders, the holidays can be everything but a celebration. Hayley ...

Addiction is an umbrella term that reflects qualities of substance use disorder, characterized by an inability to stop using a substance despite harmful consequences. However, addiction is not a ...

Nearly 19 million children in the United States have at least one parent with a substance use disorder, according to a new study published Monday in JAMA Pediatrics. And a significant number of those ...

Research on the biological basis of addiction published in Biological Psychiatry uncovers the critical role that the HDAC5 enzyme plays in gene expression in the brain's epigenetic mechanisms that ...