Clinical portfolio, informed by deep and novel synapse biology and pharmacology insights, aims to strengthen neural connections through event-driven pharmacology Lead candidate zelquistinel is ...
Functional gastrointestinal disorders (FGIDs), including irritable bowel syndrome, functional dyspepsia, and chronic visceral pain syndromes, affect a ...
How do we think, feel, remember, or move? It all depends on transmission of chemical signals in the brain, carried and released by molecular containers called vesicles. In a new study, researchers ...
In mouse brain cells, and in follow-up work involving worms and human cortical neurons, the team found that many axons ...
One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch-by clearing away protein waste at ...
How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...
A new study by Pitt researchers challenges a decades-old assumption in neuroscience by showing that the brain uses distinct transmission sites—not a shared site—to achieve different types of ...
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