Panel A shows a syphilitic chancre with a clean base and heaped-up margins. Panels B and C show scaly plaque on the palm and sole, respectively, of a patient with syphilis. Panel D shows bacteria with ...

During its second stage, syphilis may lead to a rash on one or several parts of the body. It most commonly affects the trunk, palms of the hands, and soles of the feet. The rash typically does not ...