An initial triptan prescription was linked with ischemic stroke and myocardial infarction for people with a high-risk cardiovascular profile, a case-crossover study in Denmark found. Among more than ...

Triptans are prescription medications that treat migraine attacks after they start. They cannot prevent migraine, but they can ease pain and other symptoms. Triptans calm overactive nerves during an ...

Triptan use may be associated with a low increased risk for cerebral events, such as stroke, among older adults. Older adults prescribed second-generation serotonin 5HT1B/1D-receptor agonists ...

The majority of adults with migraine seen on a headache service do not benefit from triptans because of lack of effectiveness or side effects, requiring alternate medication strategies. Investigators ...

The analysis included 64 randomized clinical trials with a total of 46,442 patients. Newer migraine pharmacotherapies appear to be less effective than triptans, according to findings from a systematic ...

A study from The BMJ indicates that the newest class of migraine drugs—which includes Pfizer’s Nurtec, AbbVie’s Ubrelvy and Eli Lilly’s Reyvow—is less effective in the acute treatment of migraines ...

Triptans have been a go-to acute migraine treatment for decades, and for many people these tried-and-true medications reliably keep full-blown migraine attacks at bay. But that’s not the case for ...

Please provide your email address to receive an email when new articles are posted on . PHILADELPHIA — The oral calcitonin gene-related peptide antagonist ubrogepant provided better pain relief than ...

Researchers urge global promotion of these triptans and recommend their inclusion in the WHO Essential Medicines List to improve accessibility and standardize care. Study: Comparative effects of drug ...

In July 2006, the FDA warned that concomitant use of a triptan (5-hydroxytryptamine [5-HT; serotonin] receptor agonists) and a selective 5-HT reuptake inhibitor (SSRI) or selective 5-HT/norepinephrine ...

In a head-to-head comparison, researchers assessed the effectiveness of migraine medications. Triptans, ergots, and antiemetics were among the most effective acute treatments for individuals with ...