Pyruvate dehydrogenase complex deficiency (PDCD) (formerly known as PDH deficiency) is an inherited inborn error of metabolism. This means that children born with ...

Endogenous pyruvate is an end-product in glycolysis and a key molecule for ATP production under aerobic and anaerobic conditions, whereas exogenous pyruvate is transferred to cells via monocarboxylate ...

The article discusses the multifactorial nature of obesity, highlighting its association with chronic low-grade inflammation, or meta-inflammation, which contributes to metabolic disorders. Pyruvate, ...