Non-viral gene therapies may ease some safety, pricing and manufacturing challenges linked to viral vectors, but experts say both approaches will still have a place.

New technology enables the insertion of a large segment of DNA into a genome, potentially expanding gene therapy treatment ...

Scientists looked at multiple techniques used to measure the modified viruses deployed in some gene therapy research and treatments. One technique, known as SEC-MALS, was the most precise and accurate ...

On a special episode (first released on June 20, 2024) of The Excerpt podcast: With the advent of CRISPR as a gene editing technology, there are new opportunities to develop breakthrough treatments ...

Researchers from Rochester Institute of Technology and the University of Rochester Medical Center have developed a new, more efficient method for gene transfer. The technique, which involves culturing ...

Researchers have used saturation genome editing to test every variant in the non coding gene RNU4 2, revealing new pathogenic ...

Delivery of therapeutic genes is essential for gene therapy. Adeno-associated viruses (AAVs) are a prime vector for carrying gene cargoes because of their superior gene segmentation flexibility and ...

One in every 10 people worldwide is impacted by a rare genetic disease but about 50% of them remain undiagnosed despite rapid increases in genetic technology and testing. Even when a person does have ...

Complexities like these make it challenging to develop broadly applicable gene therapies for these disorders. Researchers at The University of Texas at Austin now have developed an improved method of ...

Some gene therapy treatments use modified adeno-associated viruses (AAVs) like the one shown here to deliver therapeutic genetic material into a patient’s cells. In a finding with implications for one ...