Recent advances in optical physics have redefined the classical boundaries imposed by diffraction. Super-resolution imaging techniques, which once adhered strictly to the Rayleigh criterion, now ...

To unravel the complexities of biological phenomena, scientists have long relied on microscopy to visualize the intricate details of their specimens, including tissue architecture, cell morphology, ...

Existing super-resolution techniques still face considerable challenges in complex deep tissue environments. For example, Stimulated Emission Depletion (STED) microscopy relies on a doughnut-shaped ...

Researchers have shown that consumer-grade 3D printers and low-cost materials can be used to produce multi-element optical components that enable super-resolution imaging, with each lens costing less ...

When single-molecule super-resolution microscopes were first commercialized some 15 years ago, they made headlines for their ability to resolve individual molecules and structures at the nanometer ...

eDL-cSIM: An AI-driven super-resolution imaging method that captures high-quality live-cell dynamics in a single exposure, enhancing speed, resolution, and environmental robustness for advanced ...

Structured illumination microscopy (SIM) is the most preferable system for live-cell super-resolution imaging. It enables the observation of intricate subcellular dynamics. However, conventional SIM ...

Serine serves as a metabolic nexus in tumors, coordinating one-carbon metabolism, nucleotide synthesis, and redox regulation. In recent years, targeting the serine metabolic pathway, particularly the ...

A new study co-led by an Oregon Health & Science University researcher describes a breakthrough in microscopy tools that could dramatically expand how cancer biology labs study the inner workings of ...

When analyzed with a grating, the amplified Raman signals provide extremely high-resolution spectra that surpass traditional instrumental limits by employing super-resolution correlation methods.

Understanding how cells are organized and how their molecular components interact in a coordinated and cooperative manner is a central goal of modern life sciences. To answer these questions, ...

It has been over a decade since super-resolution microscopy was awarded the 2014 Nobel Prize in Chemistry, and after tremendous advancements over the years, it is on its way to becoming a standard ...